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Expanding the amino acid universe
Monday, April 23, 2001
A primary advantage of small molecules over proteins is the relatively
infinite number of building blocks available to make them compared to the 20 amino acids
that compose all proteins. But two articles in Science may lead to a more level
playing field, as separate groups of researchers at the Scripps Research Institute
published methods for incorporating modified synthetic amino acids into proteins in living
cells. The approaches have multiple potential uses, including novel protein therapeutics
with tailored properties, functional
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