Efforts to create massive libraries of the single nucleotide polymorphisms present in human populations will not, in and of themselves, result in clear correlations between individual SNPs and disease. As haplotype complexity increases, conventional techniques for detecting individual SNPs become less suited to the task.

Last week, groups from Harvard and MIT published a technique for locating SNPs on specific portions of a chromosome or gene as well as determining the presence of multiple SNPs on the same DNA strand.