BioCentury on BioBusiness,
Tools & Techniques
Monday, September 27, 1999
Although HIV cocktail therapies have decreased AIDS-related deaths over
the years, resistant strains of the virus are emerging, as highlighted by two studies
published in the Journal of the American Medical Association. Visible Genetics Inc.'s TruGene HIV-1 genotyping assay and ViroLogic Inc.'s PhenoSense HIV phenotyping
assay offer the ability to detect such treatment-resistant strains of the virus. Both
technologies have their respective strengths and weaknesses and ultimately could be used
in combination to select optimal treatment regimens.
In last week's JAMA studies, researchers at ViroLogic (South San
Francisco, Calif.) reported that 28 percent of 141 newly infected HIV patients had
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