Monday, October 19, 1998
Immune system regulation is so complex that immunotherapeutics often
can be judged only on the basis of whether or not they work in patients.
AltaRex Corp.'s Anti-idiotype Induction Therapy (AIT), for example, is
not actually an anti-idiotype antibody; it is a mouse monoclonal antibody designed to
induce the production of anti-idiotype antibodies. But in fact, the company notes that its
true mechanism of action may be antigen presentation, not the induction of anti-idiotype