Monday, December 15, 1997
As genomic sequencing generates more potential target genes with
unknown function, the need is increasing for model systems to evaluate the targets. While
mice are reasonably relevant to human physiology, genetics and gene knockouts are
difficult and time-consuming in mice. However, the zebrafish is emerging as a model system
that combines vertebrate physiology, experimentally tractable development, and ease of
generating large numbers of animals for genetic analysis (see BioCentury, Dec. 8).
Last week researchers further increased the utility of this model