BioCentury on BioBusiness,
Epigenetics: Epizyme-Celgene, Constellation-Genentech reflect different goals
Monday, April 30, 2012
A large epigenetics deal announced last week between Epizyme
Inc. and Celgene
Corp. has many similarities with January's deal between Constellation
Pharmaceuticals Inc. and Genentech
Inc. But the pacts are structured differently because the smaller
biotechs have different goals.
Epizyme is set up to remain
independent and commercialize its own products in the U.S., although the deal
has elements that could ease an acquisition by partner Celgene. In contrast,
Constellation's deal has set the company up to be acquired, with elements to
ensure some upside if Genentech does not exercise its call option (see
BioCentury, Jan. 23).
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