Senior management changes announced by Sequus Pharmaceuticals Inc. last week are part of an ongoing restructuring that illustrate the difficulties that can arise when a company shifts from a development stage company to an operating entity.

Craig Henderson, chairman and CEO, told BioCentury that he initiated searches in the first quarter for a CFO and for senior management positions in commercial operations and business development when he realized that the company needed better forecasting capabilities and a strengthened focus on oncology.