Early revenues for Metra Biosystems Inc.'s biochemical markers of bone resorption and formation provided a timely reminder that developing novel markets - as opposed to selling new products into established markets - takes concerted educational effort.

MTRA (Mountain View, Calif.) revised its product revenue estimates downward for the fiscal year ending June 30. Revenues will be $1.4-$1.7 million for the quarter and $6.2-$6.6 million