PerSeptive Biosystems Inc. lost the first round in its patent infringement litigation against Pharmacia Biotech, Sepracor Inc. and BioSepra Inc. over PBIO's Perfusion Chromatography technology.

The U.S. District Court in Boston last week ruled that PBIO had failed to name two inventors from a U.K. company, Polymer Laboratories Ltd., as co-inventors on its patents, and thus declared the patents invalid until the company amends the inventorship or appeals the ruling.