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Product Discovery & Development
Intellikine's PI3K platform reaches back to the chemistry lab at UCSF
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Sidebar: Intellikine's story
By Tim Fulmer
Senior Writer
Published on
Monday, February 27, 2012
In the early 2000s, kinase specialist and Intellikine Inc.
co-founder Kevan Shokat, professor of chemistry and cellular and molecular
pharmacology at the University
of California, San Francisco, set out to generate a comprehensive panel
of selective inhibitors of kinases in the PI3K pathway, including the PI3K
isoforms and mTOR.
Their goal was to come up with
a set of compounds and scaffolds that could be rationally modified to address
the increasingly important kinase space.
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