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Eli Lilly joins Merck, Roche with data for CETP drug for cholesterol control
CETP party of three
Published on Monday, November 21, 2011
Eli Lilly and Co. (NYSE:LLY) now has added a
third set of data aiming to show that inhibition of CETP is a viable treatment
strategy for dyslipidemia. Lilly's first Phase II data for evacetrapib,
released last week, show the highest dose more than doubled HDL while
simultaneously lowering LDL, similar to data for anacetrapib from Merck
& Co. Inc. (NYSE:MRK). A third cholesteryl ester transfer protein
inhibitor, dalcetrapib from Roche (SIX:ROG; OTCQX:RHHBY), has shown an
increase in HDL but not a decrease in LDL.
"It looks like anacetrapib and evacetrapib are
twins," Eliot Brinton, a lipidologist and director
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