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Apex takes on the shock in sepsis
Monday, March 24, 1997
£0.05) increase in MAP for
the two higher doses. The middle dose group contained a number of patients who were not
responding to catecholamines, which are used to support blood pressure and maintain kidney
function, DeAngelo said, so the effect was especially noteworthy. This group had a
baseline MAP of 59.8 mmHG, which rose to 72.5 mmHg within five minutes. For the group
given the high dose, baseline MAP was 67.6 mmHg, and rose to 78 by 15 minutes into the
infusion. At least 70 mmHG is the target
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