£0.05) increase in MAP for the two higher doses. The middle dose group contained a number of patients who were not responding to catecholamines, which are used to support blood pressure and maintain kidney function, DeAngelo said, so the effect was especially noteworthy. This group had a baseline MAP of 59.8 mmHG, which rose to 72.5 mmHg within five minutes. For the group given the high dose, baseline MAP was 67.6 mmHg, and rose to 78 by 15 minutes into the infusion. At least 70 mmHG is the target