Venture investment models come and go out of fashion, but Flagship Ventures has stuck with its thesis that novel, early stage platform companies with significant disruptive potential are the way to go. And rather than relying only on ideas coming out of academia, Flagship builds a company around many of its own ideas.

Public investors are rewarding that model in the current IPO window. In the past four years, nine Flagship portfolio companies have gone public. Five of the seven IPOs since the start of the current window in 2013 are in the black; four of those five are up over 50% from their IPO price.