BioCentury on BioBusiness,
Regulatory, clinical and other milestones
Highlights of weekly biotech stock moves
Monday, August 12, 2013
Ariad Pharmaceuticals Inc. (NASDAQ:ARIA) was down $1.43 to $18.43 last week
after disclosing that FDA denied breakthrough therapy designation for AP26113
for anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer
(NSCLC). Ariad said FDA did not grant the designation to the small molecule
dual inhibitor of ALK and EGFR because of the "relatively short follow-up"
and the small number of ALK-positive patients in the Phase I portion of a Phase
I/II trial (see B10).
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