The long and short of it

PCR is the standard method for amplifying genes used as diagnostic and prognostic markers, but it only amplifies known sequences a few hundred bases long and cannot detect unexpected sequence or structural variations. Cergentis B.V.'s TLA technology captures all insertions, deletions, inversions, SNPs and haplotypes in sequences up to 50,000 bases long, enabling sequencing of any gene in fewer iterations than existing technologies.

Thus, CEO Max van Min said, TLA has applications in multiple areas of drug discovery and development, including genetic diagnostics and oncogenetic profiling in cancer patients...