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ARTICLE | Emerging Company Profile

Eloxx: Skimming through

Eloxx redesigning old antibiotics to treat genetic diseases

January 6, 2014 8:00 AM UTC

Eloxx Pharmaceuticals Ltd. is developing compounds based on an ancient class of antibiotics that have the additional ability to treat genetic disorders caused by premature stop codons.

Roughly 12% of genetic diseases arise from nonsense mutations that insert a stop codon in mRNA coding regions and lead to truncated nonfunctional proteins...