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ClinMet metabolite panel tracks kidney disease progression, drug efficacy
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ClinMet: Metabolite monitoring
Monday, December 9, 2013
Metabolomics Inc. is using metabolomics to aid product discovery by
finding disease-specific metabolite panels that monitor drug efficacy and
provide insights about the mechanism of action of new products. Its most
advanced tool can distinguish between diabetic kidney disease patients and
healthy controls and could give companies faster readouts about how
their investigational kidney drugs are working, and how well.
The idea for the panel came from work by ClinMet's scientific
founder and SAB chair Kumar Sharma at the University
of California, San Diego, who was searching for biomarkers to track diabetic
kidney disease and determine why some patients are unresponsive to particular
treatments. Sharma is director of the Center for Renal Translational Medicine
and the Institute of Metabolomic Medicine at UCSD.
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