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Clearside's microneedles access back of eye, spare non-target tissues
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Clearside: Needle of the eye
Monday, August 5, 2013
Biomedical Inc. is using intraocular microneedles to deliver drugs
directly to the back of the eye less invasively than intravitreal or subretinal
injection. The approach lets Clearside use less drug than topical or periocular
approaches and reduce side effects by minimizing off-target drug exposure.
Current drugs for
back-of-the-eye disorders are hindered by poor delivery. Topical, periocular
and systemic delivery expose many non-target tissues to drugs. So do
invasive procedures such as ocular implants and intravitreal injection, the
latter of which may cause vitreous hemorrhage, retinal detachment or
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