Numab: Safely Killing T Cells

While several companies have started down the path of inhibiting the destructive effects of Th17 cells in rheumatoid arthritis and multiple sclerosis, Numab AG expects its bispecific antibodies will provide a greater therapeutic effect by eliminating Th17 and delta gamma T cells.

Published studies have shown T helper type 17 (Th17) and delta gamma T cells are responsible for producing inflammatory cytokines that trigger a variety of autoimmune diseases, such as interleukin-17 (IL-17), IL-21, IL-22 and granulocyte macrophage colony-stimulating factor (GM-CSF; CSF2)...