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ARTICLE | Emerging Company Profile

Ultimovacs: hTERT redux

Ultimovacs targeting multiple epitopes on the cancer target telomerase

May 13, 2013 7:00 AM UTC

Ultimovacs AS is developing a telomerase-based cancer vaccine that could treat a broader range of cancer patients than the most advanced telomerase vaccine in the clinic by delivering multiple telomerase epitopes rather than a single one.

Human telomerase reverse transcriptase (hTERT) is an attractive cancer target because it is absent from most normal cells but is expressed and active in as many as 90% of tumors, where it helps stabilize the cancer cell genome and drive long-term cell growth...