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Merganser developing hepcidin hormone peptide mimetics for beta thalassemia
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Merganser: Hip to Hep
By Michael Flanagan
Senior Writer
Published on
Monday, February 25, 2013
Merganser
Biotech Inc. is working on a treatment for beta thalassemia that can
reduce the toxic accumulation of iron. The company expects using peptide mimetics
to regulate iron absorption will be more effective than mopping excess iron up
after the fact, as marketed chelators do.
Beta thalassemia is an Orphan
genetic blood disorder caused by aberrant synthesis of hemoglobin beta chains
resulting in continuous overproduction of defective proteins, many of which are
broken down and release a glut of iron.
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