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Longevity stabilizing peptides internally with non-natural beta amino acids
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Longevity: Internal Improvements
Monday, February 25, 2013
A handful of companies are
using non-natural amino acids to improve the pharmacokinetic and metabolic
profiles of peptides and proteins, but such modifications often alter the
surface of the molecule, which can affect its binding profile and other
Biotech Inc. says its rational approach of using non-natural beta amino
acids to modify the internal structure of peptides and proteins should be
better at preserving a molecule's native biological properties and have lower
risk of causing off-target binding and toxicity.
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