BioCentury on BioBusiness,
Emerging Company Profile
Signum Dermalogix targets both mechanisms underlying rosacea
Related tables, figures and sidebars
Signum: Rosacea double play
By Michael J. Haas
Senior Writer
Published on
Monday, February 18, 2013
Therapies on the market or in development for rosacea treat
either the symptomatic flushing or the inflammatory skin lesions. Signum
Dermalogix Inc.'s lead small molecule isoprenylcysteine analog could
treat both aspects of rosacea by targeting key inflammatory pathways.
The isoprenylcysteine (IPC)
motif occurs in multiple G proteins that interact with the intracellular
domains of G protein-coupled receptors (GPCRs). These interactions regulate
multiple processes, including the secretion of pro-inflammatory cytokines.
69
words displayed of
723
words total.
To read this article, you must be an Archives subscriber. Please choose one of the options below.
All contents Copyright © 1993-2013 BioCentury Publications, Inc. ALL RIGHTS RESERVED. All use of this Web Site and its contents is governed by the BioCentury User Agreement and the BioCentury Terms of Use. The contents of this Web Site are protected under U.S. and foreign copyright and intellectual property laws, and no part of this Web Site or its contents may be photocopied, reproduced or retransmitted in any form without the written consent of BioCentury, which may be requested from Reprints/Permissions at www.biocentury.com. BioCentury®; The Bernstein Report on BioBusiness™; The BioCentury 100™; The Clear Route to ROI™; Because Real Intelligence is Hard to Find™; BCIQ™; and BioPharma's Knowledge Center™; are trademarks of BioCentury Publications, Inc., P.O. Box 1246, San Carlos, CA 94070. SciBX® and SciBX: Science-Business eXchange® are trademarks of Nature America, Inc. that are jointly used by BioCentury Publications, Inc. and Nature America, Inc.
|
Current Subscribers
If you are a current subscriber, log in below or in the upper right corner of this
page.
Log In
Subscription Option
Whether you want an individual subscription or need a global group license, we have the products,
the experience and the customer support that biopharma executives, researchers, investors, service providers,
and industry stakeholders have trusted for nearly two decades.
Let our Subscriber Services team customize the best intelligence package available in the industry to meet your needs.
Free Trial 4 Weeks of Access
Get a 4-week free trial subscription to see the important articles you are missing.
Get 4 Weeks Free
Thank You
Thanks for purchasing this article.
Please bookmark this url for future reference.
We have also sent you a confirming e-mail with a receipt and this same url for your
records.
close [ X ]