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Alzinova Alzheimer's vaccine targets highly toxic oligomer form of beta amyloid
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Alzinova: Freezing out AD
By Lev Osherovich
Senior Writer
Published on
Monday, December 17, 2012
Alzinova
AB is developing an Alzheimer's disease vaccine that uses an engineered
beta amyloid mimic to raise an immune response against highly toxic AD-associated
beta amyloid oligomers. The approach could yield a more potent protective
immune response than prior vaccines aimed at larger fibrillar aggregates of
beta amyloid.
Most therapeutic efforts in AD
have focused on blocking the production or accumulation of beta amyloid, which
over time leads to neurodegeneration and dementia.
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