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RetroSense gene therapy aims to restore vision in retinitis pigmentosa
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RetroSense: Seeing the light
By Jennifer Rhodes
Staff Writer
Published on
Monday, August 27, 2012
RetroSense
Therapeutics LLC is developing a gene therapy that is designed to
restore vision in blind retinitis pigmentosa patients. The company is sidestepping
the primary affected cells in the disease - photoreceptors - and instead is
introducing a light-activated protein to a layer of light-insensitive neurons
that sit downstream.
Retinitis pigmentosa is a
blanket term for a group of genetic disorders that lead to dystrophy and
eventual loss of photoreceptors, resulting in blindness. Vitamin A can slow
progression, but there is no treatment once the photoreceptors are lost.
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