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Oncotide SET antagonists enhance phosphatase activity, disrupt cancer signaling
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Oncotide: SETting up phosphatases
Monday, July 23, 2012
Oncotide Pharmaceuticals Inc. believes it has found a way to deactivate the
phosphorylation that is a driver of oncogenic signaling, an approach that could
provide an alternative or add-on to kinase inhibitors for blocking growth of
Rather than inhibiting kinases
to restore normal phosphorylation and reduce the signaling of up-regulated
oncogenic pathways, Oncotide is developing SET inhibitors to promote
dephosphorylation of the oncogenic signaling molecules.
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