BioCentury
ARTICLE | Emerging Company Profile

ProteoMediX: Prostate's PI3K biomarkers

ProteoMediX PI3K blood test seeks to avoid unneeded biopsies for prostate cancer

June 4, 2012 7:00 AM UTC

ProteoMedix AG is developing a multiplexed ELISA-based blood test that aims to confirm an initial PSA positive result and reduce unneeded biopsies by monitoring a quartet of biomarkers associated with alterations in PI3K signaling, a common underlying cause of prostate cancer. The company believes its ELISA could have an advantage over competing tests because it measures the activity of a tumor suppressor that has been directly linked to disease development.

While the effectiveness of PSA testing as a screening tool remains a topic of intense debate, there is widespread agreement that new diagnostics are needed to improve the specificity of prostate cancer detection (see BioCentury, Oct. 31, 2011)...