There's a well-known reason why only limited progress has been made in central nervous system diseases: it's hard. Cogent Neuroscience Inc. believes it has made a breakthrough in the use of brain tissue that will make the study of CNS disorders more fruitful.

"Classic cell culture works for many parts of the body but not for the brain," said Max Wallace, president and CEO. "First, brain tissue is post-mitotic - it has stopped dividing - so you can't take one brain cell and create a culture unless you use some gymnastics that turn them into non-natural brain cells."