Entelos: Simulating disease

While real life experiments are usually time-consuming and expensive, computer simulation holds the potential to save drug companies time and money by focusing research efforts. By building predictive, integrative models based on available scientific knowledge about a particular disease, Entelos Inc. hopes its PhysioLabs disease simulation systems will help guide experiments and increase the chances of producing approvable drugs.

"We combine information technology and life science strengths to create in silico biology," said Samuel Holtzman, president and CEO. "Using a PhysioLab, researchers can run multiple simulated experiments overnight and directly apply what they learn not only to their next day's lab work but to how they view the disease process itself."...