BioCentury
ARTICLE | Emerging Company Profile

Sensus: Controlled growth

February 17, 1998 8:00 AM UTC

To Sensus Drug Development Corp., growth hormone antagonists mean more than activists opposed to biotechnology-enhanced milk production in dairy cows. Biochemically, growth hormone antagonists are compounds that inhibit signaling through the human growth hormone receptor. Normally, growth hormone signaling leads to intracellular production of IGF-I (insulin-like growth factor-I), which exerts a range of metabolic regulatory effects.

Misregulation of this signaling pathway has been implicated in a number of metabolic diseases - diseases in which Sensus hopes to intervene...