By Ilan Zipkin
Staff Writer

To Sensus Drug Development Corp., growth hormone antagonists mean more than activists opposed to biotechnology-enhanced milk production in dairy cows. Biochemically, growth hormone antagonists are compounds that inhibit signaling through the human growth hormone receptor. Normally, growth hormone signaling leads to intracellular production of IGF-I (insulin-like growth factor-I), which exerts a range of metabolic regulatory effects.