AlphaVax: Equine virus vectors

A number of companies have tried to develop vaccine vectors based on viruses, but the method has run into several hurdles, including contamination issues related to vector manufacturing, limitations on sequential inoculation, and the ability to keep an infection from spreading in the body once the vector is delivered.

AlphaVax LLC is taking a new approach, using an avirulent form of the Venezuelan equine encephalitis virus (VEE) from which the company has developed its AlphaVax Vector System. AVS is a viral-based recombinant vector particle that serves as a vehicle for expressing immunizing genes from target pathogens...