Euroscreen: Home for orphan receptors

One of the many bottlenecks downstream from the sequencing of the human genome is the characterization of the functions of novel genes and turning them into validated therapeutic targets. A particularly alluring area is orphan G protein-coupled receptors.

Finding the ligands for these orphan receptors is the focus of Euroscreen s.a., which was formed in 1994 based on technology developed at the Institute of Interdisciplinary Research (IRIBHN) at the school of medicine of the Free University of Brussels. ...