Neugenesis: Beyond basic expression

They're not glamorous, but cost-effective expression systems for the production of recombinant proteins are at the heart of biotechnology. Familiar factories for the production of proteins include E. coli and Chinese hamster ovary (CHO) cells. Less common are systems utilizing yeast, aspergillus, insect cells, plants and transgenic animals.

Neugenesis Corp. (Honolulu, Hawaii) has developed a different system, dubbed NeuBIOS, based on a well-studied filamentous fungus, Neurospora crassa. The company believes the system will meet requirements for both competitive pricing and quality assurance, by combining the cost advantages of bacterial expression with the biological features of mammalian cell culture...