Pangaea: The body shows the way

The classic way to discover a drug is to screen thousands of compounds. Pangaea Pharmaceuticals is letting the human body do the work.

The Cambridge, Mass., company is developing naturally processed peptides to modulate immune responses, using the information selected by the body's own antigen presenting cells (APCs) and presented to T cells. This includes antigenic peptides derived from mutant self proteins or from intracellular pathogens...