Tuesday, February 20, 2001
How they did it
The International Human Genome Sequencing Consortium (IHGSC) and Celera Genomics Group (CRA, Rockville, Md.) used different approaches to sequence and assemble the human genome, but came up with qualitatively similar results.
The Consortium first broke the genome up and placed it into 100-200 kb bacterial artificial chromosome clones (BACs). Once the genome was fragmented it was sequenced using the shotgun approach to sequencing. The