Protein Renaissance

Making antibodies high-throughput

Despite improvements in humanization, antibody technology until recently still lagged behind the industrialization that was occurring in the protein field. In particular, while genomics can identify many proteins in a given family at the same time, antibodies against a given target still need to be generated one at a time.

"We waited a long time to start working on antibodies because antibody technology originally didn't match up with genomics - it wasn't high throughput," noted Craig Rosen, senior vice president of R