Monday, April 27, 1998
Cancer immunotherapy approaches attempt to recruit two general immune system responses. These are the activation of specific cytotoxic T cells (the cellular response), and the production of antibodies by B cells (the humoral response). In each case, CD4+ helper T cells provide an added layer of stimulation to the pathway, Th1 cells in the cellular case and Th2 cells in the humoral case.
Antigen presentation is the process by which cells