Skip to main content
Home > Week in Review > Preclinical Results

Chronological Index of : Preclinical Results

 Current Issue
  • BioInvent International A preclinical data

    BioInvent International AB (SSE:BINV), Lund, Sweden Product: BI-1206 Business: Cancer Indication: Treat lymphoma In mice, BI-1206 prevented tumor cell internalization of Rituxan rituximab, a chimeric mAb against CD20 …

    Published on 4/20/2015
  • AstraZeneca pl preclinical data

    AstraZeneca plc (LSE:AZN; NYSE:AZN), London, U.K. Product: Saracatinib (AZD0530) Business: Neurology Indication: Treat Alzheimers disease (AD) In a mouse model of AD, saracatinib for 4 weeks led to complete reversal of …

    Published on 4/13/2015
  • Batu Biologics preclinical data

    Batu Biologics Inc., San Diego, Calif. Product: ValloVax Business: Cancer Indication: Treat solid tumors In mouse models of melanoma, breast cancer and Lewis lung carcinoma (LLC), once-weekly subcutaneous ValloVax for 4…

    Published on 4/13/2015
  • BioBlast Pharma Ltd preclinical data

    BioBlast Pharma Ltd. (NASDAQ:ORPN), Tel Aviv, Israel Product: BB-FA Business: Neurology Indication: Treat Friedreichs ataxia In a mouse model of Friedreichs ataxia, BB-FA rescued brain and heart tissues by returning …

    Published on 4/13/2015
  • Novavax Inc preclinical data

    Novavax Inc. (NASDAQ:NVAX), Gaithersburg, Md. Product: EBOV GP vaccine, Ebola GP Vaccine Business: Infectious Indication: Prevent Ebola virus infection In non-human primates, 2 injections of 5 ug EBOV GP vaccine plus …

    Published on 4/13/2015
  • Profectus preclinical data

    Profectus BioSciences Inc., Baltimore, Md. Product: VesiculoVax Ebola vaccine Business: Infectious Indication: Prevent Ebola virus infection In rhesus macaques, a single dose of Profectus VesiculoVax Ebola vaccine given…

    Published on 4/13/2015
  • Airmid, Kineta preclinical data

    Airmid Inc., Redwood City, Calif. Kineta Inc., Seattle, Wash. Product: ShK-186 Business: Ophthalmic Indication: Treat anterior uveitis In a rat model of anterior uveitis, topical ShK-186 reduced disease severity and …

    Published on 4/6/2015
  • Anavex Life Sciences Corp preclinical data

    Anavex Life Sciences Corp. (OTCQX:AVXL), New York, N.Y. Product: ANAVEX 3-71 (formerly AF710B) Business: Neurology Indication: Treat Alzheimers disease (AD) In a mouse model of AD, ANAVEX 3-71 reversed synaptic loss in …

    Published on 3/30/2015
  • GlycoMimetics Inc preclinical data

    GlycoMimetics Inc. (NASDAQ:GLYC), Gaithersburg, Md. Product: GMI-1359 Business: Cancer Indication: Treat cancer In a mouse model of pancreatic cancer, intraperitoneal GMI-1359 plus gemcitabine significantly reduced …

    Published on 3/30/2015
  • Scancell Holdings pl preclinical data

    Scancell Holdings plc (LSE:SCLP; Xetra:SCP), Nottingham, U.K. Product: SCIB2 Business: Cancer Indication: Treat melanoma In a mouse model of melanoma, SCIB2 plus a murine CTLA-4 (CD152) immune checkpoint inhibitor …

    Published on 3/30/2015
  • BioLineRx, JHL Biotech preclinical data

    BioLineRx Ltd.(Tel Aviv:BLRX; NASDAQ:BLRX), Jerusalem, Israel JHL Biotech Inc., Zhubei, Taiwan Product: BL-9020 Business: Endocrine/Metabolic Indication: Treat Type I diabetes In a mouse model of diabetes, short-term …

    Published on 3/16/2015
  • BrainStorm preclinical data

    BrainStorm Cell Therapeutics Inc. (NASDAQ:BCLI), New York, N.Y. Product: NurOwn (MSC-NTF cells) (formerly Neurotrophic Factor Cells) Business: Neurology Indication: Treat autism In a mouse model of autism, a single …

    Published on 2/9/2015
  • arGEN-X preclinical data

    arGEN-X N.V. (Euronext:ARGX), Breda, the Netherlands Product: ARGX-110 Business: Cancer Indication: Treat chronic myelogenous leukemia (CML) In a mouse model of CML, a murine formulation of 300 g intraperitoneal ARGX-…

    Published on 1/19/2015
  • Epizyme, GlaxoSmithKline preclinical data

    Epizyme Inc. (NASDAQ:EPZM), Cambridge, Mass. GlaxoSmithKline plc (LSE:GSK; NYSE:GSK), London, U.K. Product: EPZ015666 Business: Cancer Indication: Treat mantle cell lymphoma (MCL) In mouse xenograft models of MCL, twice…

    Published on 1/19/2015
  • Global Blood Therapeutics preclinical data

    Global Blood Therapeutics Inc., South San Francisco, Calif. Product: GBT440 (formerly GTx011) Business: Hematology Indication: Treat sickle cell disease In a mouse model of sickle cell disease, twice-daily 100 mg/kg …

    Published on 1/12/2015
  • Pharnext preclinical data

    Pharnext S.A.S., Issy-Les-Moulineaux, France Product: PXT-864 Business: Neurology Indication: Treat Alzheimers disease (AD) In rodent models of AD, PXT-864 led to significant alleviation of induced cognitive deficits in…

    Published on 1/12/2015
  • Angiochem preclinical data

    Angiochem Inc., Montreal, Quebec Product: ANG4043 Business: Cancer Indication: Treat HER2-positive brain cancer In mice bearing intracranial HER2-positive tumors, twice-weekly 15 mg/kg IV ANG4043 significantly improved …

    Published on 12/15/2014
  • Glythera preclinical data

    Glythera Ltd., Newcastle upon Tyne, U.K. Product: PermaLink Business: Cancer Indication: Treat cancer In a mouse xenograft model of cancer, an antibody-drug conjugate (ADC) containing Glythera's PermaLink linker led to …

    Published on 11/3/2014
  • Novavax preclinical data

    Novavax Inc. (NASDAQ:NVAX), Gaithersburg, Md. Product: EBOV GP vaccine Business: Infectious Indication: Prevent Ebola virus infection In mice, 5 Ug EBOV GP vaccine given at baseline and day 14 led to antibody titers …

    Published on 11/3/2014
  • Peregrine preclinical data

    Peregrine Pharmaceuticals Inc. (NASDAQ:PPHM), Tustin, Calif. Product: Bavituximab (3G4) Business: Infectious Indication: Treat Ebola virus infection In vitro data showed that bavituximab specifically binds to cells …

    Published on 10/20/2014
  • Chimerix preclinical data

    Chimerix Inc. (NASDAQ:CMRX), Durham, N.C. Product: Brincidofovir (CMX001) Business: Infectious Indication: Treat Ebola virus infection Chimerix said in vitro data from studies conducted at the CDC and NIH showed that …

    Published on 10/13/2014
  • Aeolus preclinical data

    Aeolus Pharmaceuticals Inc. (OTCQB:AOLS), Mission Viejo, Calif. Product: Manganese porphyrin (AEOL 10150) Business: Other Indication: Treat acute radiation syndrome (ARS) In non-human primates, AEOL 10150 given for 60 …

    Published on 10/6/2014
  • Alnylam preclinical data

    Alnylam Pharmaceuticals Inc. (NASDAQ:ALNY), Cambridge, Mass. Product: ALN-AGT Business: Genitourinary Indication: Treat preeclampsia In a rat model of preeclampsia, subcutaneous ALN-AGT led to >90% knockdown of …

    Published on 10/6/2014
  • Novan preclinical data

    Novan Inc., Durham, N.C. Product: SB206 Business: Infectious Indication: Treat HPV infection In a rabbit model of HPV infection, topical SB206 led to complete inhibition of papilloma growth. Data were presented at the …

    Published on 9/29/2014
  • arGEN-X preclinical data

    arGEN-X N.V. (Euronext:ARGX), Breda, the Netherlands Product: ARGX-113 Business: Autoimmune Indication: Treat autoimmune diseases In non-human primates, repeat doses of ARGX-113 led to rapid and transient depletion of …

    Published on 9/22/2014

< Previous   1  2  3  4  5  Next >
Subscribe Now
Free Trial

About BioCentury

Decision-shaping business intelligence for the global biotech and pharma industry since 1993