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Boehringer Ingelheim GmbH, Ingelheim, Germany Product: Afatinib (Tomtovok) (BIBW 2992) Business: Cancer Molecular target: Epidermal growth factor receptor (EGFR); Epidermal growth factor receptor 2 (EGFR2) (HER2) (ErbB2…
Published on 1/30/2012
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Boehringer Ingelheim GmbH, Ingelheim, Germany Product: Afatinib (Tomtovok) (BIBW 2992) Business: Cancer Molecular target: Epidermal growth factor receptor (EGFR); Epidermal growth factor receptor 2 (EGFR2) (HER2) (ErbB2…
Published on 1/30/2012
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Amgen Inc. (NASDAQ:AMGN), Thousand Oaks, Calif. Takeda Pharmaceutical Co. Ltd. (Tokyo:4502), Osaka, Japan Product: AMG 386 Business: Cancer Molecular target: Angiopoietin 1 (ANG1) (ANGPT1); Angiopoietin 2 (ANG2) (ANGPT2…
Published on 1/30/2012
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NeoStem Inc. (NYSE-A:NBS), New York, N.Y. Product: AMR-001 Business: Cardiovascular Molecular target: NA Description: Autologous bone marrow-derived stem cells Indication: Treat acute myocardial infarction (AMI) …
Published on 1/30/2012
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Astex Pharmaceuticals Inc. (NASDAQ:ASTX), Dublin, Calif. Product: AT9283 Business: Cancer Molecular target: Aurora kinase A (AURKA) (Aurora-A); Aurora kinase B (AURKB) (Aurora-B) Description: Small molecule inhibitor of…
Published on 1/30/2012
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Auxilium Pharmaceuticals Inc. (NASDAQ:AUXL), Malvern, Pa. BioSpecifics Technologies Corp. (NASDAQ:BSTC), Lynbrook, N.Y. Product: Collagenase clostridium histolyticum (Xiaflex) Business: Dermatology Molecular target: …
Published on 1/30/2012
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Depomed Inc. (NASDAQ:DEPO), Menlo Park, Calif. Product: DM-1992 Business: Neurology Molecular target: NA Description: Gastric retentive extended-release formulation of levodopa/carbidopa Indication: Treat Parkinson's …
Published on 1/30/2012
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Abbott Laboratories (NYSE:ABT), Abbott Park, Ill. Product: Esprit bioresorbable vascular scaffold Business: Cardiovascular Molecular target: NA Description: Everolimus-eluting bioabsorbable scaffold made of polylactic …
Published on 1/30/2012
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Advanced Cell Technology Inc. (OTCBB:ACTC), Santa Monica, Calif. Product: MA09-hRPE cells (hESC-derived hRPE cells) Business: Ophthalmic Molecular target: Not applicable Description: Human embryonic stem cell-derived …
Published on 1/30/2012
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SynBio LLC, Moscow, Russia Xenetic Biosciences plc (LSE:XEN), London, U.K. Product: OncoHist Business: Cancer Molecular target: NA Description: Recombinant human histone H1 Indication: Treat non-Hodgkin's lymphoma (NHL)…
Published on 1/30/2012
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Genomic Health Inc. (NASDAQ:GHDX), Redwood City, Calif. Product: Oncotype DX prostate cancer assay Business: Diagnostic Molecular target: NA Description: Prostate biopsy test to guide selection of active surveillance or…
Published on 1/30/2012
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Active Biotech AB (SSE:ACTI), Lund, Sweden MediGene AG (Xetra:MDG), Martinsried, Germany Product: RhuDex Business: Autoimmune Molecular target: CD80 (B7-1) Description: Disease-modifying antirheumatic drug (DMARD) that …
Published on 1/30/2012
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Lpath Inc. (OTCBB:LPTN), San Diego, Calif. Product: Sphingomab (iSONEP) Business: Ophthalmic Molecular target: Sphingosine 1-phosphate (S1P) receptor Description: Ocular formulation of humanized mAb against sphingosine …
Published on 1/30/2012
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Lpath Inc. (OTCBB:LPTN), San Diego, Calif. Product: Sphingomab (iSONEP) Business: Ophthalmic Molecular target: Sphingosine 1-phosphate (S1P) receptor Description: Ocular formulation of humanized mAb against sphingosine …
Published on 1/30/2012
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Echo Therapeutics Inc. (NASDAQ:ECTE), Philadelphia, Pa. Product: Symphony Transdermal Continuous Glucose Monitoring System (Symphony tCGM System) Business: Diagnostic Molecular target: NA Description: Transdermal …
Published on 1/30/2012
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Active Biotech AB (SSE:ACTI), Lund, Sweden Ipsen Group (Euronext:IPN), Boulogne-Billancourt, France Product: Tasquinimod (TASQ) (ABR-215050) Business: Cancer Molecular target: Thrombospondin-1 (TSP-1) (THBS1) …
Published on 1/30/2012
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Biogen Idec Inc. (NASDAQ:BIIB), Weston, Mass. Elan Corp. plc (NYSE:ELN), Dublin, Ireland Product: Tysabri natalizumab Business: Autoimmune Molecular target: Integrin alpha(4) (VLA-4 ) (CD49D) Description: Humanized mAb …
Published on 1/30/2012
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Insmed Inc. (NASDAQ:INSM), Monmouth Junction, N.J. Product: Arikace (formerly SLIT amikacin) Business: Infectious Molecular target: Ribosomal 30S subunit Description: Sustained-release lipid inhaled targeting (SLIT) …
Published on 1/23/2012
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Memorial Hermann Healthcare System, Houston, Texas Product: Autologous human umbilical cord blood Business: Other Molecular target: NA Description: Patient's autologous human umbilical cord blood Indication: Treat …
Published on 1/23/2012
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Amgen Inc. (NASDAQ:AMGN), Thousand Oaks, Calif. Celldex Therapeutics Inc. (NASDAQ:CLDX), Needham, Mass. Product: CDX-301 Business: Transplant Molecular target: FMS-like tyrosine kinase 3 ligand (FLT3LG) Description: FMS…
Published on 1/23/2012
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Pergamum AB, Stockholm, Sweden Product: DPK-060 Business: Infectious Molecular target: NA Description: Antimicrobial peptide Indication: Treat acute external otitis Endpoint: Safety; clinical cure and microbiological …
Published on 1/23/2012
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Clavis Pharma ASA (OSE:CLAVIS), Oslo, Norway Product: Elacytarabine (CP-4055) (formerly Elacyt) Business: Cancer Molecular target: DNA polymerase Description: Lipid Vector Technology (LVT) derivative of cytarabine (Ara-…
Published on 1/23/2012
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CSL Ltd. (ASX:CSL), Melbourne, Australia Product: Factor IX-albumin fusion protein, rIX-FP (CSL654) Business: Hematology Molecular target: NA Description: Recombinant fusion protein linking human coagulation Factor IX …
Published on 1/23/2012
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Novelos Therapeutics Inc. (OTCBB:NVLT), Newton, Mass. Product: I-131-CLR1404 (HOT) Business: Cancer Molecular target: Phosphoinositide 3-kinase (PI3K) Description: Iodine-radiolabeled small molecule phosphoinositide 3-…
Published on 1/23/2012
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Bridge Bioresearch plc, London, U.K. Product: Isoniazide (BBR-012) Business: Dermatology Molecular target: NA Description: Chronic wound treatment Indication: Treat diabetic foot ulcers Endpoint: Percent reduction in …
Published on 1/23/2012