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General Electric Co. (NYSE:GE), Fairfield, Conn. Product: [18F]-flutemetamol (GE-067, AH110690, flutemetamol) Business: Diagnostic Molecular target: Beta amyloid Description: Pittsburgh compound B derivative for in vivo…
Published on 1/30/2012
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Hopital Pitie-Salpetriere, Paris, France Product: AAV1-gamma-sarcoglycan gene therapy Business: Musculoskeletal Molecular target: Not applicable Description: Adeno-associated virus (AAV) encoding the gamma-sarcoglycan …
Published on 1/30/2012
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Advaxis Inc. (OTCBB:ADXS), North Brunswick, N.J. Product: ADXS-HPV (ADXS11-001) (formerly Lovaxin C) Business: Cancer Molecular target: Not applicable Description: Live Listeria monocytogenes-expressing HPV type 16 E7 …
Published on 1/30/2012
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Genentech Inc., South San Francisco, Calif. Chugai Pharmaceutical Co. Ltd. (Tokyo:4519), Tokyo, Japan Roche (SIX:ROG; OTCQX:RHHBY), Basel, Switzerland Product: Avastin bevacizumab (RG435) Business: Cancer Molecular …
Published on 1/30/2012
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Exelixis Inc. (NASDAQ:EXEL), South San Francisco, Calif. Product: Cabozantinib (XL184) Business: Cancer Molecular target: Vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) (VEGFR-2); c-Met receptor …
Published on 1/30/2012
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Immunomedics Inc. (NASDAQ:IMMU), Morris Plains, N.J. Product: Clivatuzumab-based blood test Business: Diagnostic Molecular target: Mucin 1 (MUC1) (CD227) Description: Blood-based test that detects MUC1 Indication: …
Published on 1/30/2012
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Novartis AG (NYSE:NVS; SIX:NOVN), Basel, Switzerland Product: Everolimus (Afinitor, Certican, Zortress, Votubia) (RAD001) Business: Cancer Molecular target: Mammalian target of rapamycin (mTOR) (FRAP) (RAFT1) …
Published on 1/30/2012
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Merck & Co. Inc. (NYSE:MRK), Whitehouse Station, N.J. Sanofi (Euronext:SAN; NYSE:SNY), Paris, France Product: Gardasil Business: Infectious Molecular target: Not applicable Description: HPV types 6, 11, 16 and 18 …
Published on 1/30/2012
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Idera Pharmaceuticals Inc. (NASDAQ:IDRA), Cambridge, Mass. Product: IMO-2055, EMD 1201081 Business: Cancer Molecular target: Toll-like receptor 9 (TLR9) Description: Second-generation synthetic immune modulatory …
Published on 1/30/2012
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Novartis AG (NYSE:NVS; SIX:NOVN), Basel, Switzerland Product: LDE225 Business: Cancer Molecular target: Smoothened (SMO) Description: Smoothened (SMO) inhibitor Indication: Treat nevoid basal cell carcinoma syndrome (…
Published on 1/30/2012
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Advanced Cell Technology Inc. (OTCBB:ACTC), Santa Monica, Calif. Product: MA09-hRPE cells (hESC-derived hRPE cells) Business: Ophthalmic Molecular target: Not applicable Description: Human embryonic stem cell-derived …
Published on 1/30/2012
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Advanced Cell Technology Inc. (OTCBB:ACTC), Santa Monica, Calif. Product: MA09-hRPE cells (hESC-derived hRPE cells) Business: Ophthalmic Molecular target: Not applicable Description: Human embryonic stem cell-derived …
Published on 1/30/2012
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Genomic Health Inc. (NASDAQ:GHDX), Redwood City, Calif. Product: Oncotype DX colon cancer assay Business: Diagnostic Molecular target: NA Description: Diagnostic assay that analyzes expression of 12 genes to generate a …
Published on 1/30/2012
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DynPort Vaccine Co. LLC, Frederick, Md. Product: Recombinant botulism vaccine, rBV A/B Business: Infectious Molecular target: Not applicable Description: Recombinant botulinum neurotoxin serotypes A and B vaccine …
Published on 1/30/2012
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Infinity Pharmaceuticals Inc. (NASDAQ:INFI), Cambridge, Mass. Mundipharma International Ltd., Cambridge, U.K. Product: Saridegib (IPI-926) Business: Cancer Molecular target: Smoothened (SMO) Description: Hedgehog …
Published on 1/30/2012
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Novartis AG (NYSE:NVS; SIX:NOVN), Basel, Switzerland Product: Secukinumab (AIN457) Business: Autoimmune Molecular target: Interleukin-17 (IL-17) Description: Human mAb targeting IL-17 Indication: Treat psoriatic …
Published on 1/30/2012
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Novartis AG (NYSE:NVS; SIX:NOVN), Basel, Switzerland Product: Secukinumab (AIN457) Business: Autoimmune Molecular target: Interleukin-17 (IL-17) Description: Human mAb targeting IL-17 Indication: Treat ankylosing …
Published on 1/30/2012
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Novartis AG (NYSE:NVS; SIX:NOVN), Basel, Switzerland Product: Secukinumab (AIN457) Business: Autoimmune Molecular target: Interleukin-17 (IL-17) Description: Human mAb targeting IL-17 Indication: Treat rheumatoid …
Published on 1/30/2012
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Vanda Pharmaceuticals Inc. (NASDAQ:VNDA), Rockville, Md. Bristol-Myers Squibb Co. (NYSE:BMY), New York, N.Y. Product: Tasimelteon (VEC-162) Business: Neurology Molecular target: Melatonin MT1 receptor; Melatonin MT2 …
Published on 1/30/2012
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Genta Inc. (OTCBB:GNTA), Berkeley Heights, N.J. Daiichi Sankyo Co. Ltd. (Tokyo:4568; Osaka:4568), Tokyo, Japan Product: Tesetaxel (DJ-927) Business: Cancer Molecular target: Tubulin Description: Oral semi-synthetic …
Published on 1/30/2012
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Biogen Idec Inc. (NASDAQ:BIIB), Weston, Mass. Elan Corp. plc (NYSE:ELN), Dublin, Ireland Product: Tysabri natalizumab Business: Autoimmune Molecular target: Integrin alpha(4) (VLA-4 ) (CD49D) Description: Humanized mAb …
Published on 1/30/2012
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Atherotech Diagnostics Lab Inc., Birmingham, Ala. Product: Vertical Auto Profile (VAP) Cholesterol Test Business: Diagnostic Molecular target: NA Description: Lipid profiling test that measures 22 cholesterol components…
Published on 1/30/2012
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Spectrum Pharmaceuticals Inc. (NASDAQ:SPPI), Henderson, Nev. Bayer AG (Xetra:BAYN), Leverkusen, Germany Product: Zevalin ibritumomab tiuxetan Business: Cancer Molecular target: CD20 Description: Yttrium-90-radiolabeled …
Published on 1/30/2012
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Spectrum Pharmaceuticals Inc. (NASDAQ:SPPI), Henderson, Nev. TopoTarget A/S (CSE:TOPO), Copenhagen, Denmark Product: Belinostat (IV PXD101) Business: Cancer Molecular target: Histone deacetylase (HDAC) Description: …
Published on 1/23/2012
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Pevion Biotech AG, Ittigen, Switzerland Product: Candida vaccine (PEV7) Business: Infectious Molecular target: NA Description: Candida vaccine based on the SAP2 protein antigen, a virulence factor of vulvovaginal …
Published on 1/23/2012