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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Fatty acid synthase (FASN; FAS) Mouse studies suggest inhibiting FASN could help prevent tumor …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Guanine nucleotide binding protein q polypeptide (GNAQ; Gaq); MAS-related GPR member X1 (MRGPRX1; …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Stem cell factor receptor tyrosine kinase (c-Kit; KIT; CD117) In vitro studies have identified …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Liver cancer Prolactin (PRL); PRL receptor (PRLR) In vitro and mouse studies suggest increasing PRL …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Melanoma; breast cancer; cancer Adenosine A2A receptor (ADORA2A); CTLA-4 (CD152); ecto-5ʹ-nucleotidase (NT5E;…

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Androgen receptor (AR); prostate-specific antigen (KLK3; PSA) In vitro studies have …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Lysine-specific demethylase 4A (KDM4A; JMJD2A); KDM4B (JMJD2B) Cell culture studies suggest…

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Dermatology Dermatology Annexin A1 (ANXA1); formyl peptide receptor 1 (FPR1) Cell culture studies suggest …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Dermatology Wounds Olfactory receptor family 2 subfamily AT member 4 (OR2AT4) Cell and tissue culture studies …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Hepatic disease Hepatic disease Periostin (POSTN) Studies in mice and humans suggest inhibiting periostin could …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD) b-amyloid (Ab) Mouse studies suggest glycosphingolipid-enriched exosomes could …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Epilepsy; seizures Transient receptor potential cation channel subfamily C member 7 (TRPC7) Mouse and …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Huntington's disease (HD) Microtubule-associated protein-t (MAPT; tau; FTDP-17) In vitro and mouse …

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Ophthalmic disease Glaucoma Caspase-8 (CASP8; FLICE); toll-like receptor 4 (TLR4) Rodent studies suggest inhibiting…

    Published on 8/21/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer DNA In vitro and rat studies have identified mitochondria-targeted nanoparticle formulations of …

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Not applicable Mouse studies suggest short, ultrahigh pulses of radiation therapy could help treat …

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Chronic lymphocytic leukemia (CLL) Protein kinase Cb (PRKCB) In vitro and mouse studies suggest inhibiting …

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Prostate cancer Lactadherin (MFGE8; HMFG) Studies in patient samples and cell culture suggest inhibiting …

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Cachexia Adrenergic receptor b3 (ADRB3) In vitro and mouse studies suggest ADRB3 …

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Cachexia Parathyroid hormone-like hormone (PTHLH; PTHRP) In vitro and mouse studies …

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes Fibroblast growth factor 1 (FGF1) Mouse studies suggest recombinant FGF1 could…

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes G protein-coupled receptor 120 (GPR120; O3FAR1) Cell culture and mouse studies…

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Notch 1 (NOTCH1); g-secretase Mouse studies suggest inhibiting NOTCH1 or g-…

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Aspergillus C-type lectin domain family 7 member A (CLEC7A; DECTIN1); laminarin In vitro and …

    Published on 8/14/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Pseudomonas LecA In vitro studies identified a ligand of the Pseudomonas virulence factor lecA …

    Published on 8/14/2014

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