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Chronological Index of : Therapeutics

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  • Indication

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer AXL receptor tyrosine kinase (AXL; UFO) Mouse and cell culture studies suggest combination treatment …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Inflammatory bowel disease (IBD) Salt-inducible kinase 1 (SIK1; SIK) In vitro studies suggest …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Transforming growth factor-b1 (TGFB1) Studies in mice and patient samples suggest antagonizing …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Aurora kinase A (AURKA; aurora-A); v-myc myelocytomatosis viral related oncogene neuroblastoma derived…

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer AXL receptor tyrosine kinase (AXL; UFO); epidermal growth factor receptor (EGFR) Mouse and cell …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer CXC chemokine receptor 2 (CXCR2; IL8RB); lymphocyte antigen 6 complex locus G (LY6G; GR1) Mouse and …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Gaucher's disease DnaJ homolog subfamily B member 11 (DNAJB11; ERdj3); …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Obesity Activin A receptor type 1C (ACVR1C; ALK7) Mouse studies suggest inhibiting ALK7…

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Ebola Ebola glycoprotein GP1; Ebola glycoprotein GP2 Guinea pig and nonhuman primate studies …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Ebola Ebola glycoprotein GP1; Ebola glycoprotein GP2 Nonhuman primate studies suggest a prime-…

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS HIV gp120; HIV gp41 In vitro studies suggest a small molecule inhibiting the HIV …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS HIV gp120; HIV gp41 Studies in patient samples and in vitro suggest the broadly …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Pseudomonas Multiple virulence factor regulator (MvfR) Mouse and cell culture studies have …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation Phospholipase A2 group IVA cytosolic calcium-dependent (PLA2G4A; cPLA2-a) Rodent and cell…

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Alzheimer's disease (AD); cognitive dysfunction Not applicable Studies in humans suggest targeted, …

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Pain Aldehyde dehydrogenase 2 family mitochondrial (ALDH2) Rodent studies suggest stimulating ALDH2 could…

    Published on 9/25/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute lymphoblastic leukemia (ALL) Lysine-specific demethylase 6A (KDM6A; UTX); KDM6B (JMJD3) Cell culture …

    Published on 9/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Neurofibromin 1 (NF1); MEK; suppressor of zeste 12 homolog (SUZ12); bromodomain containing 4 (…

    Published on 9/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Junction plakoglobin (JUP) Studies in mice and patient samples suggest JUP inhibition could …

    Published on 9/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer BRAF; eukaryotic translation initiation factor 4A1 (eIF4A1); eIF4F; MEK Studies in patient samples, …

    Published on 9/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Pancreatic cancer K-Ras (KRAS) Mouse studies suggest inhibiting oxidative phosphorylation could help …

    Published on 9/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Pancreatic cancer L1 cell adhesion molecule (L1CAM; CD171) Studies in patient samples and mice suggest …

    Published on 9/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Solid tumors EPH receptor A3 (EPHA3) In vitro and mouse studies suggest EPHA3 antibodies could help treat …

    Published on 9/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Dermatology Alopecia Janus kinase (JAK) Mouse studies suggest JAK inhibitors could help treat alopecia areata (AA).…

    Published on 9/18/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Mucopolysaccharidosis a-l-iduronidase (IDUA) Feline studies suggest intrathecal IDUA …

    Published on 9/18/2014

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