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Chronological Index of : Therapeutics

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  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Autoimmune disease Osteoarthritis Matrix metalloproteinase 13 (MMP13) In vitro and rat studies identified selective…

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Brain cancer Spermidine/spermine-N1-acetyltransferase 1 (SAT1; SSAT) Studies in patients, mice and cell …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer AT rich interactive domain 1A (ARID1A); ARID1B; breast cancer 1 early onset (BRCA1); BRCA2; K-Ras (…

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Dermcidin (DCD) Cell culture studies suggest the Serinicoccus-derived natural compound seriniquinone …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Protein disulfide isomerase (PDI) Cell culture studies suggest PDI inhibitors could sensitize cancers…

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Chronic lymphocytic leukemia (CLL) Lymphotoxin-a (LTa); lymphotoxin-b receptor (LTBR); chemokine CXC motif …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Kidney cancer l-2-hydroxyglutarate dehydrogenase (L2HGDH) In vitro studies suggest agonizing L2HGDH could …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Myelodysplastic syndrome (MDS) Casein kinase 1 (CSNK1; CKI) In vitro and mouse studies suggest inhibiting …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes Not applicable Mouse and in vitro studies suggest an ethanolamine salt of the …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Diabetes; obesity G protein-coupled receptor 119 (GPR119) In vitro and mouse studies …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Infertility Neurokinin 3 receptor (TACR3; NK3R); gonadotropin-releasing hormone (GnRH) …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection Interleukin-1b (IL-1b) Mouse studies suggest altering the composition of the…

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Inflammation Inflammation Transient receptor potential vanilloid 1 (TRPV1; VR1) In vitro and mouse studies suggest …

    Published on 10/23/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Breast cancer 1 early onset (BRCA1) In vitro and mouse studies suggest small molecules that …

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer HER2 (EGFR2; ErbB2; neu) In vitro and mouse studies suggest modified versions of the antibody-…

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer G protein-coupled receptor 126 (GPR126); VEGF receptor 2 (KDR/Flk-1; VEGFR-2) In vitro, mouse and …

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Tubulin In vitro and mouse studies identified derivatives of the plant-derived compound millepachine …

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Esophageal cancer g-secretase Studies in human samples, cell culture and mice suggest inhibiting notch …

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Pancreatic cancer Branched-chain amino acids (BCAAs) Studies in human samples and mice suggest monitoring …

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension Not applicable Mouse studies suggest compounds that scavenge g-ketoaldehydes (…

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension Vanin 1 (VNN1); adrenergic receptor b1 (ADRB1) Genetic analysis and cell …

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Hyperoxaluria Alanine-glyoxylate aminotransferase (AGXT) In vitro studies suggest …

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Mucopolysaccharidosis a-l-iduronidase (IDUA) Feline studies suggest liver-directed IDUA…

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine/metabolic disease Mucopolysaccharidosis N-acetylglucosaminidase-a (NAGLU); insulin-like growth factor-2 (…

    Published on 10/16/2014
  • Therapeutics

    Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS HIV gp41 In vitro studies suggest conjugates of sapogenins, a class of antiviral …

    Published on 10/16/2014

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