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Approach Summary Licensing status Publication and contact information Assays & screens Human induced pluripotent stem (iPS) cell-derived adipocytes to screen for obesity and diabetes therapeutics Human iPS cell-…
Published on 2/2/2012
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Approach Summary Licensing status Publication and contact information Disease models Mouse model of cigarette smoke-induced emphysema A mouse model of cigarette smoke-driven emphysema could aid the development …
Published on 2/2/2012
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Approach Summary Licensing status Publication and contact information Drug platforms Depletion of tumor necrosis factor receptor superfamily member 9 (TNFRSF9; 4-1BB; CD137)+/CD4+ T cells to improve adoptive cell…
Published on 2/2/2012
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This week in techniques Approach Summary Licensing status Publication and contact information Chemistry Production of N-methylated macrocyclic peptide libraries A method for producing libraries of N-methylated …
Published on 1/26/2012
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Chimpanzee adenovirus vectors for vaccine development Human, primate and mouse studies suggest …
Published on 1/26/2012
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Next-generation prime-boost HIV vaccine A study in monkeys identified a prime and boost regimen that …
Published on 1/26/2012
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This week in techniques Approach Summary Licensing status Publication and contact information Imaging MRI detection of 2-hydroxyglutarate (2HG) to diagnosis and monitor isocitrate dehydrogenase 1 (IDH1)-mutant …
Published on 1/26/2012
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This week in techniques Approach Summary Licensing status Publication and contact information Markers Hyperpolarized 13C magnetic resonance spectroscopy (MRS) to predict tumors that will respond to anti-VEGF …
Published on 1/26/2012
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This week in techniques Approach Summary Licensing status Publication and contact information Disease models Induced pluripotent stem (iPS) cell model for Timothy syndrome A study in cell culture suggests …
Published on 1/19/2012
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This week in techniques Approach Summary Licensing status Publication and contact information Drug platforms Isoxazole compounds for pancreatic islet b cell regeneration A study in cell culture suggests 3,5-…
Published on 1/19/2012
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Approach Summary Licensing status Publication and contact information Disease models Mouse model of solute carrier family 29 member3 (SLC29A3; ENT3)-associated lysosomal storage disorders Ent3 knockout mice …
Published on 1/12/2012
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Approach Summary Licensing status Publication and contact information Disease models Mouse model of solute carrier family 29 member3 (SLC29A3; ENT3)-associated lysosomal storage disorders Ent3 knockout mice …
Published on 1/12/2012
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Approach Summary Licensing status Publication and contact information Disease models Rat model of TAR DNA binding protein 43 (TDP-43; TARDBP)-driven amyotrophic lateral sclerosis (ALS) Rats engineered to express…
Published on 1/12/2012
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Approach Summary Licensing status Publication and contact information Drug delivery Dextran-based hydrogel scaffold for burn wound skin regeneration Mouse studies suggest dextran-based hydrogels could be used as…
Published on 1/12/2012
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Approach Summary Licensing status Publication and contact information Drug platforms Crystal structure of a Fab fragment in complex with MAC-1 (CD11b-CD18) The crystal structure of a Fab bound to the integrinA …
Published on 1/12/2012
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Approach Summary Licensing status Publication and contact information Drug platforms Ebola glycoprotein (GP1)-based vaccine to prevent Ebola infection An in vitro and mouse study suggests a vaccine based on a …
Published on 1/12/2012
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Approach Summary Licensing status Publication and contact information Drug platforms Tobacco-manufactured antibodies to treat Ebola infection A study in mice suggests tobacco-manufactured mAbs could help prevent…
Published on 1/12/2012
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Approach Summary Licensing status Publication and contact information Assays & screens High throughput sequencing of tumor tissue to guide clinical trial enrollment High throughput sequencing of tumor tissue …
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Assays & screens Quantification of minimal residual disease in chronic lymphocytic leukemia (CLL) following hematopoietic stem cell transplant…
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Assays & screens Real-time classification of glioma tumors with mass spectrometry-based lipid profiling A mass spectrometry-based method for …
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Chemistry Selective arylation of imidazoles to synthesize Tasigna nilotinib and its analogs N1-selective palladium-catalyzed arylation of …
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Drug platforms Prophylactic vaccination with antibody-expressing adenoviral transgenes An adenoviral vector encoding pathogen-neutralizing …
Published on 1/5/2012
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Approach Summary Licensing status Publication and contact information Chemistry High throughput identification of chiral oligomers of pentenoic amides (COPAs) as protein ligands Screening libraries of COPAs …
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Chemistry Photocatalytic redox method for incorporating trifluoromethyl (CF3) groups into drug compounds A method of chemical synthesis …
Published on 12/15/2011
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Approach Summary Licensing status Publication and contact information Drug platforms Chemical-genetic interaction networks for target discovery against methicillin-resistant Staphylococcus aureus (MRSA) …
Published on 12/15/2011