SciBX: Science-Business eXchange
As published Thursday, October 30, 2014
By Kai-Jye Lou, Senior Writer
Redistributing BRD4 in
New clues to how inflammation leads to atherosclerosis
from a group at Harvard Medical School
point to a pivotal role for chromosomal redistribution of BRD4-a
bromodomain protein involved in chromatin
remodeling.1 The data provide insight to the mechanism of BRD4
inhibitors in the clinic for atherosclerosis, but whether the compounds offer advantages
over the standard of care still needs to be tested.
The ALS Association is allocating the first funds from its ice bucket challenge to create four new research alliances that focus on genetics and biomarkers for the disease.
Bayer is emphasizing alliances rather than money to tap into Bay Area innovation.
The NIH is taking steps to make the inclusion of both sexes in preclinical studies a standard practice.