Although GlaxoSmithKline has quietly shuttered its Center of Excellence for External Drug Discovery, the pharma maintains it is not deprioritizing early program partnerships. Rather, GSK has shifted the establishment of early partnerships to its R&D scientists.
A multi-institutional team has added more than 20 pathogens to the list of known bacteria that express the capsule polysaccharide poly-N-acetylglucosamine. The findings open up new indications for Alopexx Vaccine and Alopexx Pharmaceuticals, which are developing a vaccine and an antibody for passive immunization, respectively.
Boston researchers have discovered a blood-borne protein called growth differentiation factor 11 that can reverse age-related cardiac hypertrophy in mice. The protein could be used as a therapeutic agent once its long-term effects are understood.